In my summary lecture at the IRAS 1997 Star Island Conference on the Evolution of Morality, I reflected on the thinking of other speakers in light of my own personal experience. My remarks were organized around five questions: (1) Do worldviews matter, and how do we decide if some matter more than others? (2) What does it mean to be moral? (3) What is the relation between biology and culture? (4) How does a scientific, sociobiological description of how we have become moral fit with our own personal quest for meaning and moral guidance toward richer and fuller lives? (5) How do we test evolutionary views of the biological conditions of morality scientifically?